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Study identifier: NCT07235917 Synced from ClinicalTrials.gov · July 28, 2026
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A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea

Condition: Functional Hypothalamic Amenorrhea (FHA)  ·  Sponsor: Regeneron Pharmaceuticals

PhasePhase 2
Planned participants34
Who can joinFemale, 18 Years to 40 Years
Healthy volunteersNo

About this study

This study is researching an experimental drug called mibavademab (also called "study drug"). The study is focused on patients with a condition called Functional Hypothalamic Amenorrhea (FHA). FHA is a condition where a woman stops menstruating because the brain is not sending the correct hormonal signals to the ovaries, which then are not able to cycle and ovulate properly. The aim of the study is to see how well the study drug helps the body make the hormones necessary for ovulation and reproduction, and to assess its safety. The study is looking at several other research questions, including: * Whether the drug helps bone health * What side effects may happen from taking the study drug * How much study drug is in the blood at different times * Whether the body makes antibodies against the study drug (which could make the drug less effective or could lead to side effects)

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Administrator  ·  844-734-6643  ·  clinicaltrials@regeneron.com

Always discuss trial participation with your own doctor first.

Locations (10)

Arensia Exploratory Medicine ClinicPhoenix, Arizona, United StatesRecruiting
Focus Clinical ResearchWest Hills, California, United StatesRecruiting
Yale University School of MedicineNew Haven, Connecticut, United StatesRecruiting
Mayo Clinic FloridaJacksonville, Florida, United StatesRecruiting
Oregon Health and Science University (OHSU)Portland, Oregon, United StatesRecruiting
OBGYN Associates of ErieErie, Pennsylvania, United StatesRecruiting
Penn State Health Milton South Hershey Medical CenterHershey, Pennsylvania, United StatesRecruiting
Zillan Clinical ResearchHouston, Texas, United StatesRecruiting
University of Virginia School of MedicineCharlottesville, Virginia, United StatesRecruiting
Tidewater Clinical Research - Tidewater Physicians for WomenNorfolk, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07235917