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Study identifier: NCT07235566 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

MRG003 and Pucotenlimab to Treat Locally Advanced or Metastatic ATC/PDTC

Condition: Thyroid Cancer  ·  Sponsor: Fudan University

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a single-arm, open-label, multi-cohort, single-center phase II clinical trial designed to observe and evaluate the efficacy and safety of MRG003 (a EGFR-ADC) in combination with pucotenlimab (a PD-1 inhibitor) for the treatment of EGFR-positive unresectable recurrent or metastatic ATC/PDTC. All patients will receive the combination therapy every three weeks until disease progression or other event as defined in the protocol occurs.

This description comes directly from the study's public registry record.

Talk to the study team

Naisi Huang  ·  86-021-64175590  ·  huangnaisi@fudan.edu.cn

Yu Wang  ·  86-021-64175590  ·  neck130@sina.com

Always discuss trial participation with your own doctor first.

Locations (1)

Fudan University Shanghai Cancer CenterShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07235566