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Study identifier: NCT07234942 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7812653 in Participants With Early Symptomatic Alzheimer's Disease (eAD)

Condition: Alzheimer's Disease  ·  Sponsor: Hoffmann-La Roche

PhasePhase 1
Planned participants50
Who can joinAll sexes, 50 Years to 75 Years
Healthy volunteersNo

About this study

This study aims to evaluate the safety, tolerability, immunogenicity, pharmacokinetics, and pharmacodynamics following administration of RO7812653 in participants with eAD.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: BP45770 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728 (U.S. and Canada)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (12)

Toronto Western HospitalToronto, Ontario, CanadaRecruiting
Montreal Neurological Institute Clinical Research UnitMontreal, Quebec, CanadaRecruiting
Brain Research Center AmsterdamAmsterdam, North Holland, NetherlandsRecruiting
Hospital General de CatalunyaSant Cugat del Vallès, Barcelona, SpainRecruiting
Hospital de la Santa Creu i Sant PauBarcelona, SpainRecruiting
Hospital Universitario Reina SofiaCórdoba, SpainRecruiting
Sahlgrenska UniversitetssjukhusetMlndal, SwedenRecruiting
Karolinska UniversitetssjukhusetSolna, SwedenRecruiting
Institute of Psychiatry, Psychology and Neuroscience;Department of Old Age PsychiatryLondon, Greater London, United KingdomRecruiting
Southampton General HospitalSouthampton, Hampshire, United KingdomRecruiting
Queen Elizabeth HospitalGlasgow, Strathclyde, United KingdomRecruiting
National Hospital For Neurology and NeurosurgeryLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT07234942