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Study identifier: NCT07234890 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study to Evaluate the Effects of AV-001 on HD-induced Brain Injury.

Condition: Hemodialysis  ·  Sponsor: London Health Sciences Centre Research Institute

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Cognitive decline is increasingly recognized among patients receiving maintenance hemodialysis (HD). This can include trouble remembering, slower thinking or mentally feeling foggy. This research is being done to determine if a new medication (AV-001) can protect the brain from injury caused by hemodialysis by strengthening blood vessels in the brain and reducing inflammation. If successful, this research could lead to better protection for the brains of people undergoing regular dialysis, potentially reducing the risk of cognitive decline and stroke.

This description comes directly from the study's public registry record.

Talk to the study team

Jarrin D Penny, PhD, RN  ·  519-685-8500  ·  jarrin.penny@lhsc.on.ca

Kathy Koyle  ·  519-685-8500  ·  kathleen.koyle@lhsc.on.ca

Always discuss trial participation with your own doctor first.

Locations (1)

London Health Sciences CentreLondon, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT07234890