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Study identifier: NCT07234695 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

LEvetiracetam to Prevent Seizures in Symptomatic Alzheimer's Disease in Adults With Down Syndrome

Condition: Down Syndrome · Down Syndrome (DS) · Down Syndrome (Trisomy 21)  ·  Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

PhasePhase 3
Planned participants120
Who can joinAll sexes, 40 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate whether levetiracetam can prevent epileptic seizures in patients with Alzheimer's disease associated with Down syndrome. It will also analyze whether it can delay the neurodegeneration associated with this disease. Patients will be randomly assigned to one of two groups: one group will receive the active drug (levetiracetam), and the other will receive a placebo. Both groups will receive the treatment for 96 weeks. Each patient will participate for a total of 2 years and 5 months.

This description comes directly from the study's public registry record.

Talk to the study team

María Carmona Iragui, Doctor  ·  +34 93 556 59 56  ·  mcarmonai@santpau.cat

Diego Real de Asúa Cruzat, Doctor  ·  diego.realdeasua@salud.madrid.org

Always discuss trial participation with your own doctor first.

Locations (5)

Hospital Virgen de las NievesGranada, Andalusia, SpainNot Yet Recruiting
Fundación CITA AlzheimerDonostia / San Sebastian, Basque Country, SpainNot Yet Recruiting
Hospital Universitario Marqués de ValdecillaSantander, Cantabria, SpainNot Yet Recruiting
Hospital de la Santa Creu i Sant PauBarcelona, Catalonia, SpainRecruiting
Hospital La PrincesaMadrid, SpainNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07234695