Condition: Early Breast Cancer · Metastatic Breast Cancer · Sponsor: Institut Claudius Regaud
This trial is a translational, open-label, monocentric and prospective cohort study of participants with breast cancer aiming to create a combined ESPRESSO (= organelle properties) phenotype and spatial proteomics data collection encompassing four cohorts: * TN eBC = cohort A, * HER2+ eBC = cohort B, * Luminal eBC = cohort C, * dnMBC = cohort D. In total 1050 participants will be enrolled in the study. Laboratory analysis (including ESPRESSO technique) will be conducted on the biological specimen collected during this study. The primary objective is to describe the amount of fatty acids accumulated in lipid droplets, within the four cohorts. As a secondary objective, the analysis will expand to other organelles like lysosomal acidity and nuclear organization. The study is due to last 9 years (4 years of recruitment and 5 years of study participation)
This description comes directly from the study's public registry record.
Florence DALENC, MD, Professor · +33 5311 55 104 · Dalenc.Florence@iuct-oncopole.fr
Camille FRANCHET, MD · +33 5 31 15 64 03 · Franchet.Camille@iuct-oncopole.fr
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| Institut Universitaire du Cancer de Toulouse - Oncopole | Toulouse, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07233928