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Study identifier: NCT07232875 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

HRS 4642 Injection Combined With AG Versus Placebo Combined With AG Therapy in First-Line Advanced or Metastatic Pancreatic Cancer

Condition: KRAS G12D-Mutant Advanced or Metastatic Pancreatic Cancer in the First-line Setting  ·  Sponsor: Jiangsu HengRui Medicine Co., Ltd.

PhasePhase 3
Planned participants588
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study investigates the first-line treatment of advanced pancreatic cancer with KRAS G12D mutation. Patients were randomized 1:1 to receive either the experimental regimen HRS-4642 plus AG or the control regimen AG alone.

This description comes directly from the study's public registry record.

Talk to the study team

Hongxia Han  ·  +0518-81220121  ·  hongxia.han@hengrui.com

Always discuss trial participation with your own doctor first.

Locations (1)

Renji Hospital, Shanghai Jiao Tong University School of MedicineShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07232875