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Study identifier: NCT07232290 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase IIa Study on Flonoltinib Maleate Tablets in the Treatment of Patients With Polycythemia Vera

Condition: Polycythemia Vera (PV)  ·  Sponsor: Chengdu Zenitar Biomedical Technology Co., Ltd

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This trial adopts an open, randomized, parallel controlled, multicenter clinical trial design planning to enroll patients with polycythemia vera who are resistant/intolerant to hydroxyurea or interferon。The study divided into two stages: dose exploration stage: three dose groups are tentatively set, with three subjects in each group, totaling nine subjects in each group; Dose extension stage: Based on the safety, efficacy, and pharmacokinetic results of the comprehensive dose exploration stage, 2-3 dose groups are planned to be selected for dose extension trials.

This description comes directly from the study's public registry record.

Talk to the study team

Fangmei Wang  ·  +8613808086495  ·  fangmei.wang@zenitar.cn

Liangkun Sun  ·  +8615885742617  ·  liangkunsun@zenitar.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences (IHCAMS)Tianjin, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07232290