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Study identifier: NCT07231458 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Test a New Immunotherapy, ABX-001, Alone and in Combination With the Marketed Drug, Pembrolizumab, for the Treatment of Tumors Previously Treated With Other Therapies

Condition: Advanced Solid Tumors  ·  Sponsor: Abalos Therapeutics GmbH

PhasePhase 1
Planned participants27
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase I/Ib first-in-human, open-label, non-randomized, multicenter, multi-country study to evaluate the safety and tolerability and to establish a recommended Phase 2 dose (RP2D) as well as assess preliminary clinical activity of ABX-001 administered intravenously (IV) alone (Part A) or co-administered with pembrolizumab (Part B) in participants with refractory/relapsed advanced solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Thomas Bogenrieder, Chief Medical Officer, MD, PhD  ·  +49 173162 2682  ·  bogenrieder@abalos-tx.com

Always discuss trial participation with your own doctor first.

Locations (5)

Charite-Universitaetsmedizin Berlin - Campus Benjamin Franklin (CBF)Berlin, GermanyRecruiting
Universitaetsklinikum TuebingenTübingen, GermanyRecruiting
Vall d'Hebron Institut d'OncologiaBarcelona, SpainRecruiting
Hospital Universitario Fundacion Jimenez DiazMadrid, SpainRecruiting
The START Center for Cancer Care - CIOCCMadrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT07231458