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Study identifier: NCT07231068 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Dose-escalation and Dose-expansion Phase I/Phase II Clinical Study of Dositinib Mesylate Tablets (90-1408) in the Treatment of Locally Advanced or Metastatic Non-small Cell Lung Cancer With Positive EGFR Mutation

Condition: Non-Small Cell Lung Cancer  ·  Sponsor: Henan Genuine Biotech Co., Ltd.

PhasePhase 1/Phase 2
Planned participants153
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is an open label phase I/phase II clinical study designed to evaluate the safety, tolerability, pharmacokinetics, preliminary efficacy of Dositinib in participants of locally advanced or metastatic non-small cell lung cancer with positive EGFR mutation.

This description comes directly from the study's public registry record.

Talk to the study team

Junling Li  ·  +86 138 0117 8891  ·  drlijunling@vip.163.com

Always discuss trial participation with your own doctor first.

Locations (5)

Cancer Hospital Chinese Academy of Medical SciencesBeijing, ChinaRecruiting
Peking Union Medical College HospitalBeijing, ChinaWithdrawn
Sun Yat-sen Memorial Hospital, Sun Yat-sen UniversityGuangzhou, ChinaRecruiting
Henan Provincial Cancer HospitalZhengzhou, ChinaRecruiting
Henan Provincial People's HospitalZhengzhou, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07231068