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Study identifier: NCT07230535 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluation of Wellbeing and Patient Reported Outcomes After Open vs Robotic Mastectomy With DIEP Reconstruction

Condition: Breast Cancer, Breast Neoplasms · Breast Reconstruction · DIEP Flap Breast Reconstruction  ·  Sponsor: Beaumont Hospital

PhaseNA
Planned participants250
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Nipple-sparing mastectomy (NSM) preserves the nipple-areolar complex (NAC) and is associated with improved cosmetic outcomes, body image, and patient satisfaction compared with more ablative techniques. Its use has expanded in both therapeutic and risk-reducing settings, including ductal carcinoma in situ (DCIS) and early-stage invasive breast cancer, where the NAC is not clinically or radiologically involved. Multiple observational and cohort studies support the oncological safety of NSM in appropriately selected patients, provided meticulous surgical technique and pathological assessment are employed to minimise the risk of residual disease. Robotic-assisted NSM has emerged as a minimally invasive alternative to conventional open techniques. Robotic platforms offer enhanced three-dimensional visualisation, improved instrument articulation, and ergonomic advantages that may facilitate precise dissection while reducing surgeon fatigue. Single-port robotic systems enable NSM to be performed through a single axillary incision, potentially reducing visible scarring and postoperative discomfort while maintaining oncological principles. Early series from high-volume centres have demonstrated the technical feasibility and short-term safety of robotic NSM, with outcomes broadly comparable to open NSM and signals of potential aesthetic benefit. However, these data are largely non-randomised and derived from single-centre experiences. Despite the increasing adoption of both conventi…

This description comes directly from the study's public registry record.

Talk to the study team

Trudi Nelson Roche  ·  003531  ·  troche@rcsi.ie

Always discuss trial participation with your own doctor first.

Locations (1)

Beaumont RCSI Cancer CentreBeaumont, IrelandRecruiting

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Source record: clinicaltrials.gov/study/NCT07230535