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Study identifier: NCT07230236 Synced from ClinicalTrials.gov · July 29, 2026
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Relationship Between LS Chirp ABR and Speech-in-Noise Skills in Hidden Hearing Loss

Condition: Hidden Hearing Loss · Cochlear Synaptopathy  ·  Sponsor: Istanbul University - Cerrahpasa

PhaseN/A
Planned participants63
Who can joinAll sexes, 20 Years to 60 Years
Healthy volunteersYes

About this study

It is known that the underlying problem in Hidden Hearing Loss (HHL) is cochlear synaptopathy (CS) and that low-spontaneous-rate auditory nerve fibers play an important role in this pathology. Therefore, it is suggested that low-spontaneous-rate auditory nerve fibers are damaged in HHL. Consequently, LS CE-Chirp-evoked ABR and HINT, which assesses CS by presenting stimuli of varying intensities and characteristics to provide information about auditory nerve fibers, will be used to evaluate participants both objectively and subjectively. Aim of the study: The main aim of this study is to investigate the relationship between the amplitude and latency values obtained with LS CE-Chirp-stimulated ABR and the critical Signal-to-Noise Ratio (SNR) obtained from the Hearing in Noise Test (HINT) in individuals suspected of having HHL. Hypotheses H0: In individuals suspected of having HHL, there is no relationship between the amplitude values of waves I, III, and V obtained with LS CE-Chirp ABR at 80, 90, and 100 dBnHL and the I/V amplitude ratio and the critical SNR obtained from HINT. H1: In individuals suspected of having HHL, there is a relationship between the amplitude values of waves I, III, and V obtained with LS CE-Chirp ABR at 80, 90, and 100 dBnHL and the I/V amplitude ratio, and the critical SNR obtained from HINT. Expected Results: The study will reveal how LS CE-Chirp stimulation affects ABR results in individuals suspected of having HHL, and the relationship betwee…

This description comes directly from the study's public registry record.

Talk to the study team

Cem Yeral, MSc  ·  +90 539 402 78 46  ·  cem.yeral@ogr.iuc.edu.tr

Always discuss trial participation with your own doctor first.

Locations (1)

Istanbul University-CerrahpaşaIstanbul, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07230236