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Study identifier: NCT07228247 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase Ⅰ/Ⅱa Study of HMPL-A251 in Participants With Advanced or Metastatic HER2-expressing Solid Tumors

Condition: Solid Tumors, Adult  ·  Sponsor: Hutchmed

PhasePhase 1/Phase 2
Planned participants147
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a first-in-human (FIH), phase Ⅰ/Ⅱa, open-label, multicenter clinical study of HMPL-A251 monotherapy in adult participants with unresectable, advanced or metastatic HER2-expressing solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (15)

SCRI HealthONEDenver, Colorado, United StatesRecruiting
BRCR GlobalPlantation, Florida, United StatesRecruiting
Florida Clinical Trials Group LLC (Plantation)Plantation, Florida, United StatesRecruiting
Florida Clinical Trials Group LLC (Tamarac)Tamarac, Florida, United StatesNot Yet Recruiting
START New JerseyEast Brunswick, New Jersey, United StatesNot Yet Recruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesNot Yet Recruiting
Cleveland Clinic Taussig Cancer CenterCleveland, Ohio, United StatesRecruiting
Northwest Medical Specialties, PLLCTacoma, Washington, United StatesNot Yet Recruiting
Peking University First HospitalBeijing, ChinaRecruiting
Hunan Cancer HospitalChangsha, ChinaRecruiting
Sun Yat-sen University Cancer CenterGuangzhou, ChinaRecruiting
The First Affiliated Hospital of Anhui Medical UniversityHefei, ChinaRecruiting

+ 3 more locations — full list on the registry record.

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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07228247