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Study identifier: NCT07227948 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Repurposing Semaglutide for the Treatment of Cocaine Use Disorder

Condition: Cocaine Use Disorder  ·  Sponsor: The University of Texas Health Science Center, Houston

PhasePhase 2
Planned participants75
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), in combination with cognitive behavioral therapy (CBT) for the treatment of cocaine use disorder (CUD). This project is part of the NIH Helping to End Addiction Long-term (HEAL) initiative (https://heal.nih.gov/).

This description comes directly from the study's public registry record.

Talk to the study team

Luba Yammine, PhD  ·  (713) 486-2737  ·  Luba.Yammine@uth.tmc.edu

Jessica Vincent  ·  (713) 486-2645  ·  Jessica.N.Vincent@uth.tmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The University of Texas Health Science Center at HoustonHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07227948