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Study identifier: NCT07227493 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Open Pilon With FIBERGRAFT AERIDYAN Matrix Bioactive Glass

Condition: Open Pilon Fractures  ·  Sponsor: University of Missouri-Columbia

PhaseN/A
Planned participants45
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Open pilon fractures are challenging problems to manage. Infection rates vary from 6-30% and metaphyseal nonunion varies from 7-20%. The current recommendation for the management of open pilon fractures with bone loss is a staged approach, with internal fixation around an antibiotic spacer. Fibergraft Aeridyan Bone Graft Matrix is currently used along with other forms of allograft at our institution for filling bone voids in open pilon fractures. This is a prospective, observational study looking at the use of Fibergraft Aeridyan bone graft matrix and its efficacy in open pilon fractures. Everything in this study will be according to the standard of care at our institution other than two research only CT scans. One will be performed at the patient's 6-month visit and the other will be performed at the patient's 12-month visit. The investigators hypothesize that Fibergraft Aeridyan Bone Graft Matrix will lead to improved outcomes when compared to standard bone graft for patients by decreasing infection and nonunion rates.

This description comes directly from the study's public registry record.

Talk to the study team

Vicki L Jones, MEd  ·  573-882-7583  ·  jonesvicki@health.missouri.edu

Nash Kolb  ·  573-884-8428  ·  kolbn@health.missouri.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Missouri - ColumbiaColumbia, Missouri, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07227493