Condition: Advanced/Metastatic Non-Small Cell Lung Cancer · Carcinoma, Non-Small Cell Lung · Non-Small Cell Lung Cancer · Sponsor: Pfizer
This study is being done to learn more about a new medicine called PF-08634404 and how it works when used with other cancer medicines in people who have advanced solid tumors. An advanced solid tumor is a type of cancer that has spread beyond its original location and cannot be removed by surgery or cured with standard treatments. To join in the study, participants must: * Be 18 years or older * Participants with advanced non-small cell lung cancer (NSCLC), a type of lung cancer that has spread The study will look at: * Whether PF-08634404 is safe to use with other cancer medicines. * What side effects may happen. A side effect is anything the medicine does to your body that is not part of treating your disease. * Whether the combination of PF-08634404 and other cancer medicines can help treat solid tumors. The study has different parts, each testing PF-08634404 with a different cancer medicine: * Part A will test PF-08634404 with a medicine called sigvotatug vedotin. * Part B of the study will look at how well the new medicine PF-08634404 works when used together with another medicine. Participants will receive the study medicines through an intravenous (IV) infusion (injected into the vein) at the study clinic. All treatments will take place at clinical trial sites, where trained medical staff will monitor participants during and after each visit.
This description comes directly from the study's public registry record.
Pfizer CT.gov Call Center · 1-800-718-1021 · ClinicalTrials.gov_Inquiries@pfizer.com
Always discuss trial participation with your own doctor first.
| Highlands Oncology Group, PA | Fayetteville, Arkansas, United States | Recruiting |
| Highlands Oncology Group, PA | Rogers, Arkansas, United States | Recruiting |
| Highlands Oncology Group, PA | Springdale, Arkansas, United States | Recruiting |
| Providence Medical Foundation | Fullerton, California, United States | Recruiting |
| Providence St. Jude Medical Center - Virginia K. Crosson Cancer Center and Infusion Center | Fullerton, California, United States | Recruiting |
| Providence St. Jude Medical Center | Fullerton, California, United States | Recruiting |
| Valkyrie Clinical Trials (Additional Site Pharmacy Storage Suite) | Los Angeles, California, United States | Recruiting |
| Valkyrie Clinical Trials | Los Angeles, California, United States | Recruiting |
| Mission Community Hospital (Satellite Site) | Panorama City, California, United States | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Denver, Colorado, United States | Recruiting |
| BRCR Medical Center Inc. | Coral Springs, Florida, United States | Recruiting |
| Mid Florida Hematology and Oncology Center | Orange City, Florida, United States | Recruiting |
+ 61 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07227298