Condition: Post Operative Pain · Total Hip Arthroplasty · Sponsor: Medical University of South Carolina
This randomized, double-blind controlled trial investigates whether intraoperative intravenous methadone (0.15 mg/kg based on ideal body weight) reduces acute postoperative pain and opioid consumption in patients undergoing elective total hip arthroplasty under spinal anesthesia with mepivacaine. The primary outcome is patient-reported pain on a visual analog scale (VAS) 30-60 minutes after arrival in the post-anesthesia care unit (PACU). Secondary outcomes include opioid use, pain scores over time, incidence of nausea/vomiting, and quality of recovery. A total of 162 subjects will be enrolled at MUSC surgical sites.
This description comes directly from the study's public registry record.
Haley Nitchie, MHA · 843-792-1869 · nitchie@musc.edu
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| Medical University of South Carolina | Charleston, South Carolina, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07227064