Condition: Clinical High Risk for Psychosis (CHR) · Sponsor: Monument Therapeutics Limited
The goal of this clinical trial is to learn how tests undertaken by people at high risk of developing psychosis (aged 17 to 30 years old) change when those people are given the study drug MT1988 daily for 8 weeks. This will help identify tests that could be used in later trials developing treatments for symptoms in people at high risk of developing psychosis, to measure whether those new treatments are effective. The main question this trial aims to answer is: Can any of the tests (biomarkers) used in this study detect changes in participants dosed with one of two different dose levels of MT1988? Researchers will compare the results from two dose levels of MT1988 to a placebo group. Researchers do not expect to see the test results change in participants taking placebo and this will be compared to changes expected in test results in participants taking MT1988. Participants will: * take a dose of MT1988 or placebo twice per day for 8 weeks * attend clinic appointments every two weeks to undertake assessments * report any side effects they experience to the researchers
This description comes directly from the study's public registry record.
Sheryl Caswell · +447539430768 · info@monumenttx.com
Always discuss trial participation with your own doctor first.
| University of California, Irvine | Irvine, California, United States | Recruiting |
| University of California | Los Angeles, California, United States | Recruiting |
| University of California, San Francisco | San Francisco, California, United States | Recruiting |
| Yale University Conneticut Mental Health Center | New Haven, Connecticut, United States | Recruiting |
| Beth Israel Deaconess Medical Center | Boston, Massachusetts, United States | Recruiting |
| Washington University | St Louis, Missouri, United States | Recruiting |
| Northwell Health | Glen Oaks, New York, United States | Recruiting |
| Columbia University | New York, New York, United States | Recruiting |
| Icahan School of Medicine at Mount Sinai | New York, New York, United States | Recruiting |
| University of North Carolina at Chapel Hill | Chapel Hill, North Carolina, United States | Recruiting |
| Ohio State University | Columbus, Ohio, United States | Recruiting |
| Prevention Science Institute | Eugene, Oregon, United States | Recruiting |
+ 3 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07226895