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Study identifier: NCT07226765 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

Condition: Obstructive Sleep Apnea  ·  Sponsor: Amgen

PhasePhase 3
Planned participants250
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersNo

About this study

This Phase 3 clinical trial is designed to evaluate the efficacy and safety of maridebart cafraglutide compared to placebo over a 52-week period in adults with obstructive sleep apnea (OSA) who are not on PAP therapy and are living with overweight or obesity.

This description comes directly from the study's public registry record.

Talk to the study team

Amgen Call Center  ·  866-572-6436  ·  medinfo@amgen.com

Always discuss trial participation with your own doctor first.

Locations (54)

Valley Clinical TrialsNorthridge, California, United StatesRecruiting
Peninsula Research AssociatesRolling Hills Estates, California, United StatesRecruiting
Teradan Clinical TrialsBrandon, Florida, United StatesRecruiting
Destiny Research CenterPalmetto Bay, Florida, United StatesRecruiting
Clinical Research Center Of FloridaPompano Beach, Florida, United StatesRecruiting
NeuroTrials ResearchAtlanta, Georgia, United StatesRecruiting
Basil ClinicalLaurelton, New York, United StatesRecruiting
Monroe Biomedical ResearchMonroe, North Carolina, United StatesRecruiting
CTI Clinical Research CenterCincinnati, Ohio, United StatesRecruiting
FutureSearch Trials of NeurologyAustin, Texas, United StatesRecruiting
Epic Medical Research - DeSotoDeSoto, Texas, United StatesRecruiting
Sleep Therapy & Research CenterSan Antonio, Texas, United StatesRecruiting

+ 42 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07226765