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Study identifier: NCT07225777 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Sex Differences in Neurobehavioral Response to THC

Condition: Cannabis Use Disorder  ·  Sponsor: Medical University of South Carolina

PhasePhase 2
Planned participants40
Who can joinAll sexes, 21 Years to 45 Years
Healthy volunteersNo

About this study

This study investigates sex differences in reward processing following acute THC administration in adults with cannabis use disorder (CUD). Using multimodal neuroimaging (MRS and fMRI), the study will assess glutamate levels in the nucleus accumbens and striatal BOLD response to monetary reward anticipation. Participants will complete two counterbalanced dosing sessions (oral THC 40 mg vs. placebo).

This description comes directly from the study's public registry record.

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Locations (1)

Medical University of South CarolinaCharleston, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07225777