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Study identifier: NCT07225764 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CaOx Stone Prevention

Condition: Kidney Stones  ·  Sponsor: Icahn School of Medicine at Mount Sinai

PhasePhase 4
Planned participants80
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This single-center randomized controlled trial at Mount Sinai West will enroll 80 patients undergoing percutaneous nephrolithotomy for calcium oxalate stones. Participants will be randomized to receive either empiric therapy or selective therapy guided by 24-hour urine evaluation. The primary outcome is change in calcium oxalate supersaturation at 4 weeks, aiming to determine whether empiric therapy can provide outcomes comparable to selective therapy while simplifying access to prevention.

This description comes directly from the study's public registry record.

Talk to the study team

Blair Gallante, MPH  ·  631-991-1159  ·  blair.gallante@mountsinai.org

Mantu Gupta, MD  ·  212-241-1272  ·  mantu.gupta@mountsinai.org

Always discuss trial participation with your own doctor first.

Locations (1)

Mount Sinai WestNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07225764