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Study identifier: NCT07225127 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

Condition: Bladder Cancer · Recurrent Bladder Cancer · Non-muscle Invasive Bladder Cancer (NMIBC)  ·  Sponsor: University of Washington

PhaseN/A
Planned participants408
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Bladder cancer is the most common urinary tract cancer and the 6th most common cancer in the US. Yet bladder cancer research is underfunded relative to other common cancers. As a result, bladder cancer care is prone to evidence gaps that produce decision uncertainty for both patients and clinicians. The Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer Study 2 (CISTO2) has the potential to fill these critical evidence gaps, change care pathways for the management of NMIBC (non-muscle-invasive bladder cancer), and provide for personalized, patient-centered care. The purpose of CISTO2 is to conduct a large prospective study that directly compares the impact of bladder sparing therapies versus bladder removal in recurrent high-grade NMIBC patients on financial toxicity, clinical outcomes and patient and caregiver experience using standardized patient-reported outcomes (PROs).

This description comes directly from the study's public registry record.

Talk to the study team

Sung Min Kim  ·  206-210-4040  ·  cistorc@uw.edu

Always discuss trial participation with your own doctor first.

Locations (6)

H. Lee Moffitt Cancer Center & Research InstituteTampa, Florida, United StatesRecruiting
University of IowaIowa City, Iowa, United StatesRecruiting
University of North CarolinaChapel Hill, North Carolina, United StatesRecruiting
The Ohio State UniversityColumbus, Ohio, United StatesNot Yet Recruiting
Vanderbilt University Medical CenterNashville, Tennessee, United StatesRecruiting
Fred Hutch/University of Washington Cancer ConsortiumSeattle, Washington, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07225127