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Study identifier: NCT07225114 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging

Condition: Breast Cancer · Kidney Neoplasms · Liver Neoplasms  ·  Sponsor: UNC Lineberger Comprehensive Cancer Center

PhasePhase 2
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This is a 4-arm, single-center study involving 40 participants. Ten healthy volunteers will be enrolled for system imaging optimization, and thirty (30) patients with previously identified lesions in the breast, liver, or kidney-based on prior ultrasound or cross-sectional imaging-will be imaged. Recruitment will be conducted such that ten patients are included from each anatomic region. The fourth arm will consist of 10 healthy volunteers who will be imaged to allow optimization of imaging parameters. Optimization is is required again due to the use of a different ultrasound system employing a new imaging technique. Parameters such as frame rate, power, depth of imaging, and linear translation rate will be adjusted during this process. The primary objectives of the study are to assess the sensitivity and specificity of Contrast Enhanced Super-Resolution (CESR) imaging in evaluating known lesions in the breast, liver, and kidney. These results will be compared with pathological findings. The secondary objectives are to compare the sensitivity and specificity of CESR imaging with those of traditional B-mode ultrasound in differentiating malignant from benign lesions in these same organs.

This description comes directly from the study's public registry record.

Talk to the study team

Desma Jones  ·  (919) 843-9463  ·  desma_jones@med.unc.edu

Markeela Lipscomb  ·  (919) 843-3670  ·  markeela_lipscomb@med.unc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The University of North CarolinaChapel Hill, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07225114