Condition: CRC (Colorectal Cancer) · Sponsor: City of Hope Medical Center
The EpiDRIVE study aims to identify cfDNA-based epigenetic determinants of response in metastatic colorectal cancer (mCRC) patients treated with EGFR- or VEGF-targeted therapy. By integrating 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) profiling, this study seeks to develop a predictive biomarker panel capable of differentiating responders from non-responders to targeted therapy.
This description comes directly from the study's public registry record.
Ajay Goel, PhD · 626-359-8111 · ajgoel@coh.org
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| City of Hope Medical Center | Duarte, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07224841