Condition: CRC (Colorectal Cancer) · Sponsor: City of Hope Medical Center
The EpiCORE study aims to identify cfDNA-based epigenetic markers predictive of response to first-line chemotherapy (FOLFOX or FOLFIRI) in metastatic colorectal cancer (mCRC). By integrating 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) profiling, this study seeks to establish a non-invasive biomarker panel capable of distinguishing responders from non-responders.
This description comes directly from the study's public registry record.
Ajay Goel, PhD · 6263598111 · ajgoel@coh.org
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| City of Hope Medical Center | Duarte, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07224815