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Study identifier: NCT07224529 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland Dysfunction

Condition: Meibomian Gland Dysfunction (MGD)  ·  Sponsor: University of Alabama at Birmingham

PhasePhase 4
Planned participants48
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This research study evaluates a prescription eye drop called Vevye® (cyclosporine 0.1%) for adults who have meibomian gland dysfunction (MGD), a common eye condition that can cause dry, irritated, or burning eyes. If you join the study, after a short "run-in" period using artificial tears, you will receive Vevye twice a day for about 24 weeks (approximately six months). During that time you will attend several clinic visits where your eye symptoms, lid health, tear film, and meibomian gland function will be assessed. The goal is to learn whether Vevye improves symptoms (like eye dryness or irritation) and signs (such as changes on the eye's surface or lid margins) of MGD. You will also be monitored for safety and comfort of the eye drop. The information obtained from this study may help determine whether this treatment is beneficial for people with this condition and contribute to future care options. Participation is voluntary and you may stop at any time.

This description comes directly from the study's public registry record.

Talk to the study team

Sindhu Gurrala, BDS, MPH  ·  (205) 934-6734  ·  SOeyes@uab.edu

UAB Optometry Clinical Research  ·  205-975-3881  ·  sgurral2@uab.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Alabama at Birmingham, School of Optometry, Clinical Eye Research FacilityBirmingham, Alabama, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07224529