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Study identifier: NCT07224321 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes

Condition: Type 1 Diabetes Mellitus  ·  Sponsor: Mannkind Corporation

PhasePhase 2
Planned participants100
Who can joinAll sexes, 10 Years to 17 Years
Healthy volunteersNo

About this study

INHALE-1st is a Phase 2, single-arm, multi-center, clinical study evaluating the safety and efficacy of Afrezza in combination with subcutaneously-injected basal insulin (BI) for youth 10 to \<18 years old with newly diagnosed stage 3 type 1 diabetes (T1D). The study will also evaluate the effect of an Afrezza plus BI reigmen on participant and parent/legally authorized representative satisfaction. Participants will be followed for 13 weeks during the main phase followed by an optional Extension Phase for participants continuing to use Afrezza in combination with BI for up to 26 weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Jennifer Pleitez  ·  818-661-5032  ·  jpleitez@mannkindcorp.com

Always discuss trial participation with your own doctor first.

Locations (10)

Children's Hospital Los AngelesLos Angeles, California, United StatesRecruiting
University of California San FranciscoSan Francisco, California, United StatesRecruiting
Barbara Davis Center for Diabetes Young Adult ClinicAurora, Colorado, United StatesRecruiting
Yale UniversityNew Haven, Connecticut, United StatesRecruiting
University of FloridaGainesville, Florida, United StatesRecruiting
Indiana UniversityIndianapolis, Indiana, United StatesRecruiting
Joslin Diabetes CenterBoston, Massachusetts, United StatesRecruiting
University of Oklahoma Health Sciences CenterOklahoma City, Oklahoma, United StatesNot Yet Recruiting
Baylor College of MedicineHouston, Texas, United StatesRecruiting
University of VirginiaCharlottesville, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07224321