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Study identifier: NCT07224243 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Impact of Intraoperative Oxygenation Practices on Patient Outcomes

Condition: Surgeries Undergoing General Anesthesia  ·  Sponsor: Frederic T Billings IV

PhaseNA
Planned participants54000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This multicenter, cluster-randomized, cluster-crossover clinical trial evaluates the impact of three intraoperative FiO2 (Fraction of Inspired Oxygen) oxygenation strategies-lower (FiO₂ 0.21-0.40), intermediate (FiO₂ 0.40-0.80), and higher (FiO₂ 0.80-1.00)-on postoperative organ injury and mortality in adult surgical patients. The trial aims to determine the optimal oxygenation strategy to improve perioperative outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Tracie Baker, CCRA  ·  6158751852  ·  tracie.d.baker@vumc.org

Always discuss trial participation with your own doctor first.

Locations (4)

University of Michigan HospitalAnn Arbor, Michigan, United StatesNot Yet Recruiting
Nebraska Medical CenterOmaha, Nebraska, United StatesRecruiting
Vanderbilt University Medical CenterNashville, Tennessee, United StatesRecruiting
University of Utah Huntsman Cancer InstituteSalt Lake City, Utah, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07224243