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Study identifier: NCT07223242 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Tailored Exercise Training Study Among Adults With HFpEF

Condition: HFpEF - Heart Failure With Preserved Ejection Fraction · Diabetic Cardiomyopathies  ·  Sponsor: University of Texas Southwestern Medical Center

PhasePhase 2/Phase 3
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Heart failure with preserved ejection fraction (HFpEF) is associated with a high morbidity and mortality burden. There are limited pharmacological options available for the treatment of HFpEF. Exercise intolerance (EI) is the cardinal symptom of HFpEF, which manifests as dyspnea and fatigue. EI leads to functional deconditioning and reduced quality of life (QOL), both of which elevate risk of death and hospitalization in patients with HFpEF. Supervised exercised training is associated with improvements in exercise capacity and QOL in adults with HFpEF. However, supervised exercise has not been widely utilized for the treatment of HFpEF due to logistical and fiscal barriers. This study will investigate the effects of a remote exercise training intervention on exercise capacity and skeletal muscle composition in patients with HFpEF, or those at risk for it. In addition, it will compare four different lifestyle interventions for their effects on exercise capacity.

This description comes directly from the study's public registry record.

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Locations (1)

University of Texas Southwestern Medical CenterDallas, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07223242