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Study identifier: NCT07222488 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)

Condition: Bladder Cancer · Urinary Bladder Neoplasms  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 1/Phase 2
Planned participants45
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Researchers are looking for new ways to treat high-risk non-muscle invasive bladder cancer (HR NMIBC). NMIBC is cancer in the tissue that lines the inside of the bladder and has not spread to the bladder muscle or outside of the bladder. In standard treatment for HR NMIBC, doctors first remove the tumor with a procedure called transurethral resection of the bladder tumor (TURBT). Researchers want to learn if using MK-3120, the study medicine, can treat HR NMIBC after TURBT. The goal of this study is to learn about the safety of MK-3120 and if people tolerate it.

This description comes directly from the study's public registry record.

Talk to the study team

Toll Free Number  ·  1-888-577-8839  ·  Trialsites@msd.com

Always discuss trial participation with your own doctor first.

Locations (15)

Michael G Oefelein Clinical Trials ( Site 0005)Bakersfield, California, United StatesRecruiting
Carolina Urologic Research Center ( Site 0006)Myrtle Beach, South Carolina, United StatesRecruiting
Medizinische Universität Wien ( Site 0021)Vienna, State of Vienna, AustriaRecruiting
UZ Gent ( Site 0031)Ghent, Oost-Vlaanderen, BelgiumRecruiting
CHU de Quebec - Hopital de l'Enfant-Jesus ( Site 0011)Québec, Quebec, CanadaRecruiting
Gustave Roussy ( Site 0041)Villejuif, Val-de-Marne, FranceRecruiting
European Interbalkan Medical Center ( Site 0051)Thessaloniki, GreeceRecruiting
Rabin Medical Center ( Site 0062)Petah Tikva, IsraelRecruiting
Centro Ricerche Cliniche di Verona ( Site 0072)Verona, Veneto, ItalyRecruiting
Nederlands Kanker Instituut Antoni van Leeuwenhoek (NKI AVL) ( Site 0081)Amsterdam, North Holland, NetherlandsRecruiting
Akershus Universitetssykehus ( Site 0091)Lorenskog, Akershus, NorwayRecruiting
Hospital Universitario Virgen de la Victoria ( Site 0111)Málaga, Andalusia, SpainRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07222488