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Study identifier: NCT07221929 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Exercise-priming of CBT for Depression: the CBT+ Trial

Condition: Major Depressive Disorder  ·  Sponsor: University of Wisconsin, Madison

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This study investigates the effects of intentionally sequencing aerobic exercise immediately prior to cognitive behavioral therapy (CBT) to determine its effects on mechanisms of CBT (i.e., working alliance, behavioral activation). To assess the utility of this treatment augmentation, investigators will conduct a randomized controlled trial involving 100 adults with Major Depressive Disorder who will watch a nature documentary while either resting quietly ( 'CalmCBT') or exercising at a moderate intensity ('ActiveCBT') immediately prior to 8 weekly sessions of CBT.

This description comes directly from the study's public registry record.

Talk to the study team

Madeleine Connolly, PhD  ·  (608) 890-0154  ·  mconnolly5@wisc.edu

Jeni Lansing, PhD

Always discuss trial participation with your own doctor first.

Locations (1)

University of WisconsinMadison, Wisconsin, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07221929