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Study identifier: NCT07221838 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia Gravis Treated With Ravulizumab

Condition: Generalized Myasthenia Gravis · gMG  ·  Sponsor: Alexion Pharmaceuticals, Inc.

PhasePhase 4
Planned participants75
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a prospective, multicenter single arm study designed to evaluate the effectiveness and safety of a predefined oral corticosteroids (OCS) tapering schedule to reduce OCS use in adult participants with acetylcholine receptor positive (AChR+) generalized myasthenia gravis (gMG) being treated with intravenous ravulizumab.

This description comes directly from the study's public registry record.

Talk to the study team

Alexion Pharmaceuticals, Inc. (Sponsor)  ·  1-855-752-2356  ·  clinicaltrials@alexion.com

Always discuss trial participation with your own doctor first.

Locations (12)

Research SiteChicago, Illinois, United StatesNot Yet Recruiting
Research SiteSchaumburg, Illinois, United StatesNot Yet Recruiting
Research SiteNeptune City, New Jersey, United StatesNot Yet Recruiting
Research SiteRaleigh, North Carolina, United StatesRecruiting
Research SiteKnoxville, Tennessee, United StatesNot Yet Recruiting
Research SiteBochum, GermanyNot Yet Recruiting
Research SiteMilan, ItalyNot Yet Recruiting
Research SiteNaples, ItalyNot Yet Recruiting
Research SiteRome, ItalyNot Yet Recruiting
Research SiteIbaraki, JapanNot Yet Recruiting
Research SiteKitakyushu-shi, JapanNot Yet Recruiting
Research SiteKumamoto, JapanNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07221838