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Study identifier: NCT07221539 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Restoration of Consciousness With Ultrasonic Deep Brain Stimulation During Anesthetic Sedation

Condition: Mental Function  ·  Sponsor: University of Michigan

PhaseNA
Planned participants168
Who can joinAll sexes, 18 Years to 40 Years
Healthy volunteersYes

About this study

The purpose of this study is to see if mental functions take place during different levels of anesthesia using two commonly used drug (propofol and dexmedetomidine) and will include low-intensity focused ultrasound pulsation (LIFUP) to stimulate specific areas of the brain while undergoing functional Magnetic Resonance Imaging (fMRI or "brain imaging"), which shows areas in the brain involved in thinking at different depths of anesthesia. That is, ultrasound is being used to stimulate the brain and multiple pictures will be taken of the brain. As a result of this study, we expect to gain a deeper understanding of mental function during different levels of anesthesia, and to evaluate if the use of ultrasonic brain stimulation accelerates return to consciousness.

This description comes directly from the study's public registry record.

Talk to the study team

Aaron Ellis  ·  734-647-8129  ·  aaronel@med.umich.edu

Amy McKinney  ·  734-647-8129  ·  adrongo@med.umich.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of MichiganAnn Arbor, Michigan, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07221539