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Study identifier: NCT07221227 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

Condition: Non-alcoholic Fatty Liver Disease  ·  Sponsor: GlaxoSmithKline

PhasePhase 3
Planned participants1200
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The purpose of this study is to assess the safety and efficacy of efimosfermin alfa in the resolution of steatohepatitis and improvement of liver-related clinical outcome compared to placebo in individuals with MASH and biopsy-confirmed F2- or F3-stage fibrosis.

This description comes directly from the study's public registry record.

Talk to the study team

US GSK Clinical Trials Call Center  ·  877-379-3718  ·  GSKClinicalSupportHD@gsk.com

EU GSK Clinical Trials Call Center  ·  +44 (0) 20 89904466  ·  GSKClinicalSupportHD@gsk.com

Always discuss trial participation with your own doctor first.

Locations (91)

GSK Investigational SiteChandler, Arizona, United StatesRecruiting
GSK Investigational SiteTucson, Arizona, United StatesRecruiting
GSK Investigational SiteLittle Rock, Arkansas, United StatesRecruiting
GSK Investigational SiteArcadia, California, United StatesRecruiting
GSK Investigational SiteCovina, California, United StatesRecruiting
GSK Investigational SiteFolsom, California, United StatesRecruiting
GSK Investigational SiteLos Angeles, California, United StatesRecruiting
GSK Investigational SiteMontclair, California, United StatesRecruiting
GSK Investigational SiteRiverdale, California, United StatesRecruiting
GSK Investigational SiteSan Diego, California, United StatesRecruiting
GSK Investigational SiteSanta Maria, California, United StatesRecruiting
GSK Investigational SiteVan Nuys, California, United StatesRecruiting

+ 79 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07221227