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Study identifier: NCT07221149 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

Condition: Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma  ·  Sponsor: Bristol-Myers Squibb

PhasePhase 2/Phase 3
Planned participants690
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety and efficacy of Pumitamig in combination with chemotherapy versus Nivolumab in combination with chemotherapy in participants with previously untreated advanced or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma

This description comes directly from the study's public registry record.

Talk to the study team

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com  ·  855-907-3286  ·  Clinical.Trials@bms.com

First line of the email MUST contain NCT # and Site #.

Always discuss trial participation with your own doctor first.

Locations (161)

Local Institution - 0284Phoenix, Arizona, United StatesNot Yet Recruiting
Local Institution - 0437Los Angeles, California, United StatesNot Yet Recruiting
University of California, Irvine (UCI) Health - UC Irvine Medical CenterOrange, California, United StatesRecruiting
Local Institution - 0428San Francisco, California, United StatesNot Yet Recruiting
Florida Cancer Specialists - SouthFort Myers, Florida, United StatesRecruiting
Local Institution - 0433Jacksonville, Florida, United StatesNot Yet Recruiting
Florida Cancer Specialists - NorthSt. Petersburg, Florida, United StatesRecruiting
Local Institution - 0246Tampa, Florida, United StatesNot Yet Recruiting
Emory UniversityAtlanta, Georgia, United StatesRecruiting
Local Institution - 0379Chicago, Illinois, United StatesNot Yet Recruiting
Local Institution - 0268Iowa City, Iowa, United StatesNot Yet Recruiting
Local Institution - 0259Rochester, Minnesota, United StatesNot Yet Recruiting

+ 149 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07221149