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Study identifier: NCT07220473 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Tirzepatide to Slow Biological Aging

Condition: Aging · LONGEVITY 1  ·  Sponsor: The University of Texas Medical Branch, Galveston

PhasePhase 2
Planned participants90
Who can joinAll sexes, 55 Years to 70 Years
Healthy volunteersNo

About this study

This pilot clinical study aims to investigate the potential effects of tirzepatide on biological aging in older adults. In this novel study, 90 adults aged 55-70 years with an indication for tirzepatide weight-loss therapy will be randomized to receive either tirzepatide 2.5 mg subcutaneously (SC) weekly or no drug for 24 weeks, followed by 12 weeks off the drug. Since tirzepatide is already recognized as a highly effective weight-loss agent in this population, the primary focus will not be on measuring weight loss. Instead, the study will document the effects of tirzepatide on markers of aging, physical function, and overall health.

This description comes directly from the study's public registry record.

Talk to the study team

Lamonne Crutcher  ·  (409)772-1619  ·  lmcrutch@utmb.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Texas Medical BranchGalveston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07220473