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Study identifier: NCT07219212 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

Condition: Squamous Cell Carcinoma of Head and Neck  ·  Sponsor: Johnson & Johnson Enterprise Innovation Inc.

PhasePhase 1
Planned participants45
Who can joinAll sexes, 18 Years to 74 Years
Healthy volunteersNo

About this study

This global, open-label, single arm, phase 1b study aims to learn more about whether a treatment called JNJ-90301900 is safe and effective when injected directly into tumors, along with standard chemotherapy and radiation therapy, for participants with head and neck squamous cell cancer (HNSCC; a type of solid tumor that begins in outer tissue layer of the mouth \& throat).

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (17)

University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting
City of HopeDuarte, California, United StatesRecruiting
Mayo ClinicJacksonville, Florida, United StatesRecruiting
Moffit Cancer centerTampa, Florida, United StatesRecruiting
Emory UniversityAtlanta, Georgia, United StatesRecruiting
Boston Medical CenterBoston, Massachusetts, United StatesRecruiting
Montefiore Medical CenterThe Bronx, New York, United StatesRecruiting
University of North Carolina at Chapel HillChapel Hill, North Carolina, United StatesRecruiting
University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
Hopital De La Cavale BlancheBrest, FranceRecruiting
Centre Oscar LambretLille, FranceRecruiting
Hopital La TimoneMarseille, FranceRecruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07219212