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Study identifier: NCT07218809 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

Condition: Epithelial Ovarian Cancer  ·  Sponsor: AstraZeneca

PhasePhase 3
Planned participants1100
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The intention of the study is to demonstrate superiority of AZD5335 versus standard of care by assessment of progression-free survival (PFS) in women with high-grade, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer, expressing high or low FRα levels.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (299)

Research SiteBirmingham, Alabama, United StatesRecruiting
Research SiteLittle Rock, Arkansas, United StatesNot Yet Recruiting
Research SiteLa Jolla, California, United StatesNot Yet Recruiting
Research SiteWashington D.C., District of Columbia, United StatesRecruiting
Research SiteFort Lauderdale, Florida, United StatesNot Yet Recruiting
Research SiteGainesville, Florida, United StatesRecruiting
Research SiteJupiter, Florida, United StatesRecruiting
Research SiteMiami, Florida, United StatesRecruiting
Research SiteWeston, Florida, United StatesNot Yet Recruiting
Research SiteChicago, Illinois, United StatesNot Yet Recruiting
Research SiteEvanston, Illinois, United StatesNot Yet Recruiting
Research SitePeoria, Illinois, United StatesRecruiting

+ 287 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07218809