Condition: Pulmonary Arterial Hypertension · Sponsor: Merck Sharp & Dohme LLC
Researchers are looking for more ways to treat PAH. In PAH, the blood vessels in the lungs become thick and narrow, which makes it harder for blood to flow. This causes high blood pressure in the lungs and overworks the heart. PAH can make it hard to breathe and be active. Some standard (usual) treatments for PAH can treat symptoms of PAH but do not stop PAH from getting worse. Sotatercept is a study medicine designed to treat PAH. It is a targeted therapy, which is a treatment that works on certain proteins that play a role in causing PAH. This is a long-term follow-up (LTFU) study. People who took part in certain other studies testing sotatercept for PAH may be able to join this study. The goal of this study is to learn about the long-term safety of sotatercept and if people tolerate it when taken with standard PAH treatment over a longer period of time.
This description comes directly from the study's public registry record.
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| Pulmonary Associates, PA ( Site 1008) | Phoenix, Arizona, United States | Active Not Recruiting |
| Arizona Pulmonary Specialists ( Site 1010) | Scottsdale, Arizona, United States | Recruiting |
| University of Arizona ( Site 1006) | Tucson, Arizona, United States | Recruiting |
| University of California San Diego Health ( Site 1002) | La Jolla, California, United States | Active Not Recruiting |
| UC Irvine Health Medical Center ( Site 1086) | Orange, California, United States | Active Not Recruiting |
| UC Davis - Medial Center ( Site 1064) | Sacramento, California, United States | Recruiting |
| UCSF Helen Diller Medical Center at Parnassus Heights ( Site 1019) | San Francisco, California, United States | Active Not Recruiting |
| Jeffrey S. Sager, MD Medical Corporation ( Site 1060) | Santa Barbara, California, United States | Active Not Recruiting |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center ( Site 1028) | Torrance, California, United States | Active Not Recruiting |
| University of Colorado Hospital ( Site 1013) | Aurora, Colorado, United States | Active Not Recruiting |
| George Washington University Medical Faculty Associates ( Site 1025) | Washington D.C., District of Columbia, United States | Recruiting |
| Mayo Clinic Jacksonville ( Site 1045) | Jacksonville, Florida, United States | Active Not Recruiting |
+ 117 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07218029