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Study identifier: NCT07217717 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

Condition: Pancreatic Ductal Adenocarcinoma (PDAC)  ·  Sponsor: SOFIE

PhasePhase 3
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multi-site, open-label, non-randomized, single dose study to assess the clinical utility of \[¹⁸F\]FAPI-74 PET/CT in the detection of metastatic disease in individuals with pathologically confirmed pancreatic ductal adenocarcinoma. Following screening, using a standardized administration protocol and dose, participants will undergo \[¹⁸F\]FAPI-74 PET/CT screening. SOC procedures and interventions will be captured during 3 months +/-14 days post injection. The primary objective is to evaluate the sensitivity and specificity of such \[¹⁸F\]FAPI-74 PET/CT using a composite SOT panel. The maximum expected duration of the trial is approximately 24 months from first patient screening to last patient SOC follow up. The participants will be followed-up for safety for 24 to 72 hours after the dose of \[¹⁸F\]FAPI-74 PET/CT.

This description comes directly from the study's public registry record.

Talk to the study team

Alex Osipova  ·  1-800-753-5368  ·  Alex.osipova@sofie.com

Bridget Adams  ·  1-800-753-5368  ·  bridget.adams@sofie.com

Always discuss trial participation with your own doctor first.

Locations (15)

Helios CR Inc./RadNetCerritos, California, United StatesRecruiting
City of Hope National Cancer CenterDuarte, California, United StatesRecruiting
Hoag Memorial HospitalIrvine, California, United StatesRecruiting
UCLALos Angeles, California, United StatesRecruiting
Stanford UniversityStanford, California, United StatesRecruiting
Moffit Cancer CenterTampa, Florida, United StatesRecruiting
Indiana University Health University HospitalIndianapolis, Indiana, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
UMass/ShieldsWorcester, Massachusetts, United StatesRecruiting
Mayo Clinic RochesterRochester, Minnesota, United StatesRecruiting
Icahn School of Medicine at Mount SinaiNew York, New York, United StatesNot Yet Recruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07217717