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Study identifier: NCT07217054 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Colonic Tissue Biopsy Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis or REM Sleep Behavior Disorder

Condition: PARKINSON DISEASE (Disorder) · Parkinson · Parkinson s Disease  ·  Sponsor: CND Life Sciences

PhaseN/A
Planned participants40
Who can joinAll sexes, 40 Years to 99 Years
Healthy volunteersNo

About this study

The goal of this observational study is to learn whether tissue samples taken from the colon during routine colonoscopy can detect signs of Parkinson's disease or REM Sleep Behavior Disorder (RBD). The main question it aims to answer is: Can doctors find a protein called alpha-synuclein in colon tissue samples from people with Parkinson's disease and RBD? Currently, Parkinson's disease is diagnosed by observing symptoms like tremors and movement problems and RBD by loss of muscle atonia during REM sleep, but by then the disease has already progressed significantly. Earlier detection could help doctors start treatment sooner.

This description comes directly from the study's public registry record.

Talk to the study team

Christina Wagner  ·  203-481-0315  ·  cwagner@ddabranford.com

Always discuss trial participation with your own doctor first.

Locations (1)

Digestive Disease AssociatesBranford, Connecticut, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07217054