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Study identifier: NCT07216820 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Interscalene vs Phrenic-sparing Blocks in Obesity and Effect of Maximum Inspiratory Pressure

Condition: Shoulder Surgery · Obesity  ·  Sponsor: University of North Carolina, Chapel Hill

PhaseNA
Planned participants68
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn whether a phrenic-sparing nerve block can lower early breathing problems after shoulder surgery in adults with obesity, and whether a simple breathing-strength test (maximum inspiratory pressure, MIP) helps identify who is at higher risk. The main questions are: Does the phrenic-sparing approach reduce breathlessness or oxygen need in the recovery room (30-60 minutes after arrival)? Do patients have similar pain control and opioid use compared with the standard interscalene block (ISB)? Are there any breathing-related complications or unplanned admissions within 24 hours? Researchers will compare the phrenic-sparing block (infraclavicular + distal suprascapular) to the standard ISB, both commonly used at UNC. Participants will: Have a quick MIP breath test before surgery (and, if age ≥65, a brief thigh muscle ultrasound). Be randomly assigned to receive either the standard ISB or the phrenic-sparing block (both ultrasound-guided and part of routine care). Receive usual anesthesia/surgery; have a brief recovery check at 30-60 minutes (breathlessness score, oxygen use, oxygen level). Have pain medicines recorded from anesthesia start to PACU discharge; the team may review the chart up to 24 hours and make a short follow-up call (24-48 hours).

This description comes directly from the study's public registry record.

Talk to the study team

Monika Nanda  ·  919-966-5136  ·  mnanda@aims.unc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of North Carolina HospitalsChapel Hill, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07216820