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Study identifier: NCT07215585 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL

Condition: Large B-cell Lymphoma  ·  Sponsor: AstraZeneca

PhasePhase 3
Planned participants420
Who can joinAll sexes, 65 Years to 130 Years
Healthy volunteersNo

About this study

The purpose of this study is to measure the efficacy and safety of R-mini-CHOP × 2 followed by AZD0486 compared with R-mini-CHOP × 6 in elderly or unfit participants newly diagnosed with LBCL.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (68)

Research SiteClayton, AustraliaNot Yet Recruiting
Research SiteMacquarie University, AustraliaWithdrawn
Research SiteMelbourne, AustraliaRecruiting
Research SiteNedlands, AustraliaNot Yet Recruiting
Research SiteWaratah, AustraliaNot Yet Recruiting
Research SiteAntwerp, BelgiumWithdrawn
Research SiteBrussels, BelgiumNot Yet Recruiting
Research SiteGhent, BelgiumRecruiting
Research SiteLeuven, BelgiumRecruiting
Research SiteRoeselare, BelgiumSuspended
Research SiteYvoir, BelgiumRecruiting
Research SitePorto Alegre, BrazilRecruiting

+ 56 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07215585