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Study identifier: NCT07213349 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Daridorexant for Alzheimer Disease Prevention

Condition: Alzheimer Disease (AD)  ·  Sponsor: Douglas Mental Health University Institute

PhasePhase 2
Planned participants240
Who can joinAll sexes, 50 Years to 90 Years
Healthy volunteersYes

About this study

This study will evaluate whether daridorexant, a DORA sleep medication, can support brain health by promoting the clearance of proteins linked to the development and progression of Alzheimer's disease. The trial is preventive and is open to participants who do not have Alzheimer's disease dementia, regardless of whether or not they experience sleep problems.

This description comes directly from the study's public registry record.

Talk to the study team

Jennifer Tremblay-Mercier, MSc  ·  855-888-4485  ·  prevenir.alzheimer@douglas.mcgill.ca

Nolan-Patrick Cunningham, BA  ·  15147616131  ·  nolan-patrick.cunningham.comtl@ssss.gouv.qc.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Centre StoP-Alzheimer (Douglas Mental Health University Institute - Research Centre)Montreal, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT07213349