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Study identifier: NCT07213063 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effects of Chronic Creatine and Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Oxidative Stress, Inflammation, Muscle Strength, and Body Composition in Individuals With Down Syndrome

Condition: Down Syndrome (DS) · Supplementation  ·  Sponsor: Universidad de Burgos

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Purpose: This study will test whether 8 weeks of creatine and HMB supplementation can improve muscle strength, body composition, balance, and overall health in people with Down syndrome. Participants will also receive nutrition tips during the study. Who can participate: People with Down syndrome who can perform basic physical tasks. Must provide consent from the participant and legal guardian. What participants will do: Take creatine (3 g/day) and HMB (3 g/day) or placebo for 8 weeks. Complete tests for muscle strength, balance, and cognitive function. Undergo body composition scans and give blood samples for health markers. Timing: All tests and blood samples are taken before and after each 8-week period. Importance: Results will help determine if creatine and HMB can safely improve strength, balance, and overall health in people with Down syndrome.

This description comes directly from the study's public registry record.

Talk to the study team

Alba Abia Heras, Nutrition and Dietetics  ·  615 18 16 15  ·  aheras@uemc.es

Always discuss trial participation with your own doctor first.

Locations (1)

Universidad de BurgosBurgos, Burgos, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT07213063