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Study identifier: NCT07212595 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Biomarker and Renal Angina Validation to Assess Heart-Kidney Outcomes After Amino Acid Therapy

Condition: Acute Kidney Injury · Mechanical Ventilation  ·  Sponsor: Dana Fuhrman

PhasePhase 2
Planned participants30
Who can joinAll sexes, N/A to 18 Years
Healthy volunteersNo

About this study

The goal of the BRAVE-HEART study is to learn if an amino acid infusion can reduce the risk of developing acute kidney injury after cardiac surgery in children. The main questions it aims to answer are: 1. Does an amino acid infusion decrease the number of participants with acute kidney injury? 2. Does an amino acid infusion decrease the number of days that participants are on a ventilator after cardiac surgery? Researchers will compare amino acids to a placebo (a look-alike substance that contains no drug) to see if amino acids decrease the number of participants with acute kidney injury. Participants will receive an amino acid or placebo infusion for up to 72 hours starting during cardiac surgery and only while in the operating room or the intensive care unit.

This description comes directly from the study's public registry record.

Talk to the study team

Kelli Krallman, RN, BSN, MS  ·  513-636-4837  ·  kelli.krallman@cchmc.org

Always discuss trial participation with your own doctor first.

Locations (1)

Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07212595