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Study identifier: NCT07211958 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation

Condition: Acute Myeloid Leukemias  ·  Sponsor: Syndax Pharmaceuticals

PhasePhase 3
Planned participants468
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to assess if adding revumenib to standard chemotherapy improves outcomes in participants with AML with certain genetic mutations compared to chemotherapy alone. The study will also assess the safety of adding revumenib to chemotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Syndax Pharmaceuticals  ·  781-419-1400  ·  clinicaltrials@syndax.com

Always discuss trial participation with your own doctor first.

Locations (83)

Clinical Trial SiteMelbourne, Victoria, AustraliaRecruiting
Clinical Trial SiteNedlands, Western Australia, AustraliaRecruiting
Clinical Trial SitePerth, Western Australia, AustraliaRecruiting
Clinical Trial SiteGosford, AustraliaRecruiting
Clinical Trial SiteWollongong, AustraliaRecruiting
Clinical Trial SiteSankt Pölten, Lower Austria, AustriaRecruiting
Clinical Trial SiteGraz, Styria, AustriaRecruiting
Clinical Trial SiteLeoben, Styria, AustriaRecruiting
Clinical Trial SiteLinz, AustriaRecruiting
Clinical Trial SiteGhent, BelgiumRecruiting
Clinical Trial SiteFortaleza, Paraná, BrazilRecruiting
Clinical Trial SiteBarretos, São Paulo, BrazilRecruiting

+ 71 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07211958