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Study identifier: NCT07211178 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

Condition: Breast Cancer · TNBC - Triple-Negative Breast Cancer · HR Positive/HER-2 Negative Breast Cancer  ·  Sponsor: Tempus AI

PhaseN/A
Planned participants900
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersNo

About this study

For patients with breast cancer, it's important to find any remaining cancer cells after they've had their main treatment. Even a few cells, called minimal residual disease (MRD), can lead to the cancer coming back later. A way to find these cells is by looking for tiny bits of cancer DNA that are shed into the blood. This is called circulating tumor DNA (ctDNA). A simple blood test, often called a liquid biopsy, can detect this ctDNA. This research aims to see if finding this cancer DNA in the blood can help predict if a patient's cancer will return. It also may help find out if the treatment is working. Ultimately, the results of this research may help doctors better manage breast cancer and develop new and improved tests and treatments.

This description comes directly from the study's public registry record.

Talk to the study team

GEMINI Breast Clinical Study Manager  ·  (833) 514-4187  ·  gemini-breast@tempus.com

Always discuss trial participation with your own doctor first.

Locations (14)

Birmingham Hematology AssociatesBirmingham, Alabama, United StatesRecruiting
PIH Health Whittier HospitalWhittier, California, United StatesRecruiting
Cleveland Clinic FloridaWeston, Florida, United StatesRecruiting
Southern Illinois Hospital ServicesCarbondale, Illinois, United StatesRecruiting
Cancer Care Specialist of IllinoisO'Fallon, Illinois, United StatesRecruiting
Goshen Center for Cancer CareGoshen, Indiana, United StatesRecruiting
Trinity HealthAnn Arbor, Michigan, United StatesRecruiting
Oncology Hematology AssociatesSpringfield, Missouri, United StatesRecruiting
Cancer Care Specialist of RenoReno, Nevada, United StatesRecruiting
Summit Medical GroupFlorham Park, New Jersey, United StatesRecruiting
University of Cincinnati Medical CenterCincinnati, Ohio, United StatesRecruiting
Nashville GeneralNashville, Tennessee, United StatesRecruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07211178