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Study identifier: NCT07211035 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effect of the Amplifi™ Vein Dilation System on Outflow Vein Dilation and AV Fistula Maturation (AMPLIFI-1)

Condition: End Stage Kidney Disease (ESRD)  ·  Sponsor: Amplifi Vascular, Inc.

PhaseNA
Planned participants160
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The AMPLIFI-1 Study is a prospective, multicenter pivotal clinical trial designed to evaluate the safety and effectiveness of the Amplifi™ Vein Dilation System in patients requiring distal arteriovenous fistula (AVF) creation for hemodialysis. The study has two cohorts: a randomized controlled (RC) cohort of patients with suitable cephalic veins (≥2.5 mm) randomized 2:1 to Amplifi treatment plus AVF creation versus standard AVF creation alone, and a non-randomized small vein cohort (NRC) of patients with borderline veins (1.7 to \<2.5 mm) treated with Amplifi therapy followed by AVF creation.

This description comes directly from the study's public registry record.

Talk to the study team

Erdie De Peralta Vice President, Regulatory and Clinical Affairs, Master of Arts  ·  19784080949  ·  edeperalta@amplifivascular.com

Always discuss trial participation with your own doctor first.

Locations (2)

Brigham Women's HospitalBoston, Massachusetts, United StatesRecruiting
Flow VascularHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07211035