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Study identifier: NCT07210775 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Topical Imiquimod Treatment of Oral Dysplasia

Condition: Oral Dysplasia · Leukoplakia Oral · Leukoplakia  ·  Sponsor: University of Southern California

PhasePhase 1/Phase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to determine the effectiveness of imiquimod in treating oral dysplasia in adult patients. Imiquimod 5% cream could be a safe and practical treatment for oral epithelial dysplasia (a precancerous change in the mouth). The main questions it aims to answer are: 1. Does imiquimod help to make the lesions smaller and make the abnormal cell changes less severe? 2. How can we make this treatment safer and more feasible? Participants will apply topical imiquimod cream to treat the oral dysplasia and receive two follow-up biopsies after the treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Anette Vistoso Monreal  ·  (213) 821-0148  ·  avistoso@ostrow.usc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

OralCare PreCancer and Pain ClinicLos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07210775